By Anthony W. Czarnik
The swift enlargement of combinatorial chemistry has renewed curiosity in solid-phase natural synthesis, a mode that lends itself good to making and screening huge numbers of lead compounds. Solid-Phase natural Syntheses, quantity 1 is the 1st quantity in a sequence that might be up to date every year, filling a spot within the latest chemical literature. offering details formerly unavailable from a unmarried source, this sequence is devoted to delivering researchers within the box with proven and proven equipment for the solid-phase synthesis of attention-grabbing and biologically appropriate molecules. Solid-phase equipment will almost regularly be invented for program in combinatorial natural synthesis. to satisfy those particular wishes, Solid-Phase natural Syntheses, quantity 1 specializes in a unmarried kind of man made transformation comprehensive on reliable help, and shows how approaches are optimized to paintings with a structurally-wide number of reagents. Written via famous leaders within the box who evaluate and try all chemical protocols ahead of book, natural adjustments are equipped through form of compound synthesized and response kind. For the 1st time, experimental info for confirmed solid-phase artificial molecules are accumulated in one, priceless source. Solid-Phase natural Syntheses, quantity 1 presents combinatorial chemists and researchers in natural chemistry and medicinal chemistry with the instruments and descriptive protocols to accomplish syntheses of wanted compounds utilizing various sturdy helps and reagents.