New PDF release: Drug Discovery: A History

By Walter Sneader

ISBN-10: 0470015535

ISBN-13: 9780470015537

ISBN-10: 0471899798

ISBN-13: 9780471899792

Written through a number one authority with a very good popularity and talent for writing an exceptional narrative, Drug Discovery: A History is a much cry from easily an inventory of chemical constructions.

This full of life new textual content considers the origins, improvement and background of medications that generate excessive media curiosity and feature an enormous social and fiscal influence on society.

Set inside of a large old, social and cultural context, it offers extended assurance of pre-twentieth century medicinal drugs, the massive advances made within the 20th century and the most recent advancements in drug examine.

Hallmark features:

  • Up-to-the-minute info in drug research
  • Vignettes of certain and strange info, and anecdotes
  • Discusses drug prototypes from all sources
  • More entire than different volumes on heritage of drug discovery

From the reviews:

"...an very good bibliographic source for these attracted to the heritage papers that function the basis for discovery of particular drug entities." magazine OF clinical CHEMISTRY, June 2006

"...a very complete evaluate of drug improvement. it's going to be at the shelf on any aspiring pharmacist, medicinal chemist, or individual drawn to the background of healing agents." magazine OF CHEMICAL schooling, February 2006

"...a very readable and heavily researched book..." CHEMISTRY & undefined, October 2005

Content:
Chapter 1 advent (pages 1–7):
Chapter 2 The Prehistoric interval (pages 6–11):
Chapter three Pre?Hellenic Civilisations (pages 12–17):
Chapter four Greece and Rome (pages 18–23):
Chapter five The Arab international (pages 24–31):
Chapter 6 Herbals (pages 32–40):
Chapter 7 Chemical drugs (pages 41–73):
Chapter eight Systematic drugs (pages 74–87):
Chapter nine Alkaloids (pages 88–105):
Chapter 10 Non?Alkaloidal Plant items (pages 106–114):
Chapter eleven Plant Product Analogues and Compounds Derived from Them (pages 115–150):
Chapter 12 The Origins of Hormone treatment (pages 151–154):
Chapter thirteen Neurohormones (pages 155–163):
Chapter 14 Peptide Hormones (pages 164–172):
Chapter 15 intercourse Hormones (pages 173–178):
Chapter sixteen Adrenal Cortex Hormones (pages 179–184):
Chapter 17 Prostaglandins (pages 185–187):
Chapter 18 Hormone Analogues (pages 188–225):
Chapter 19 supplementations (pages 226–247):
Chapter 20 Antimetabolites (pages 248–268):
Chapter 21 Blood and organic items (pages 269–286):
Chapter 22 Antibiotics (pages 287–318):
Chapter 23 Antibiotic Analogues (pages 319–340):
Chapter 24 Pharmacodynamic brokers from Micro?Organisms (pages 341–348):
Chapter 25 Analogues of Pharmacodynamic brokers from Fungi (pages 349–354):
Chapter 26 the 1st man made medications and Their Analogues (pages 355–374):
Chapter 27 medicines Originating from the Screening of Dyes (pages 375–402):
Chapter 28 medicinal drugs Originating from the Screening of natural chemical compounds (pages 403–431):
Chapter 29 medicines found via Serendipitous Observations concerning people (pages 432–437):
Chapter 30 medicines stumbled on via Serendipity within the Laboratory (pages 438–445):
Chapter 31 Concluding feedback (pages 446–447):

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Additional resources for Drug Discovery: A History

Sample text

The al-Tasrif, however, was written for physicians, not apothecaries; hence much of the text was concerned with the use of drugs. This was covered strictly within the confines of humoral medicine, with all products evaluated in terms of their qualities, namely hot, cold, dry or wet. As an admirer of Galen, its author did not hesitate to compound a variety of ingredients together in the expectation that the body will select the most appropriate one. This was carried to an extreme in the 4th volume where he elaborated upon the seven-stage preparation and the 84 ingredients of the famous antidote known as the Great Theriac.

In this he warned the public of the dangers surrounding the administration of Jesuits’ bark by the unskilled. Cunningly, he suggested that this remedy should not altogether be condemned, but nowhere did he even hint that he himself had used it! The book boosted his reputation, and King Charles II awarded him a knighthood and issued letters patent appointing Talbor as his physician in ordinary. This was done despite fierce criticism from the College of Physicians, angered at the appointment of an unqualified practitioner.

There were also about 90 minerals, including calamine, mercury and sulfur. Passed down the generations, De Materia Medica strongly influenced Arab physicians after the fall of Rome. 10,11 Pliny the Elder Unlike many of the prominent figures in Greek medicine, Pliny the Elder (23–79) was a Roman. He compiled an encyclopaedic work dealing with around 900 herbs, The Natural History. Written with somewhat less rigour and care for detail than was De Materia Medica, it reflected the use of folk medicines by those who could not afford the services of a physician and was more readable than the herbal of Dioscorides.

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Drug Discovery: A History by Walter Sneader


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