By National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Ocean Studies Board, Committee on Marine Biotechnology: Biomedical Applications of Marine Natural Products

ISBN-10: 0309083427

ISBN-13: 9780309083423

Document from the Committee on Marine Biotechnology discussing the biomedical functions of marine usual items. Softcover.

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Journal of Biomedical Materials Research 32:143-147. , L. Aravind, E. V. Koonin, M. T. Suzuki, A. Hadd, L. P. Nguyen, S. B. Jovanovich, C. Gates, R. A. Feldman, and E. F. DeLong. 2000. Bacterial bacteriorhodopsin: evidence for light-driven proton pumping in the sea. Science 289:1902-1906. , E. N. Spudich, J. L. Spudich, M. Leclerc, and E. F. DeLong. 2001. Proteorhodopsin phototrophy in the ocean. Nature 411:786-789. Bentley, R. 1997. Microbial secondary metabolites play important roles in medicine; prospects for discovery of new drugs.

Nelson, R. A. Clayton, M. L. Gwinn, R. J. Dodson, D. H. Haft, E. K. Hickey, J. D. Peterson, L. Umayam, S. R. Gill, K. E. Nelson, T. D. Read, H. Tettelin, D. Richardson, M. D. Ermolaeva, J. Vamathevan, S. Bass, H. Qin, I. Dragoi, P. Sellers, L. McDonald, T. Utterback, R. D. Fleishmann, W. C. Nierman, O. White, et al. 2000. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406:477-483. Janes, K. , P. Calvo, and M. J. Alonso. 2001. Polysaccharide colloidal particles as delivery systems for macromolecules.

Fifteen other compounds isolated from marine organisms, many of which were discovered with the assistance of the National Cancer Institute’s Natural Products Branch, are in clinical trials or earlier stages of drug development. One anti-inflammatory substance, a partially purified pseudopterosin extracted from the Caribbean sea whip, the soft coral Pseudopterogorgonia elisabethae, has been licensed for use in skin-care products. Hydroxyapatite, from marine coral, has FDA approval to be implanted into fractures or voids of human bones to aid in regrowth and repair.

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MARINE BIOTECHNOLOGY IN THE TWENTY-FIRST CENTURY by National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Ocean Studies Board, Committee on Marine Biotechnology: Biomedical Applications of Marine Natural Products

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