Mechanosensitive Ion Channels, Part A by Owen P. Hamill (Eds.) PDF

By Owen P. Hamill (Eds.)

ISBN-10: 0121533581

ISBN-13: 9780121533588

Membranes are crucial mobile organelles. They not just outline cells and different organelles, but in addition are serious within the phone functionality through selectively regulating the passage of molecules via performing as a matrix for different signaling molecules, and as conduits of knowledge move among the exterior surroundings and the mobile inside. This sequence used to be initially further in 1970 and has in view that supplied a scientific, accomplished, and rigorous method of particular themes proper to the learn of mobile membranes. every one quantity is a visitor edited compendium of membrane biology. This sequence has been a mainstay for training scientists and scholars drawn to this severe box of biology. Articles coated within the quantity comprise The Mechanical homes of Bilayers; Molecular Dynamic Modeling of MS Channels; constructions of the Prokaryotic Mechanosensitive; Channels MscL and MscS; 3.5 Billion Years of Mechanosensory Transduction: constitution and serve as of Mechanosensitive Channels in Prokaryotes; Activation of Mechanosensitive Ion Channels by means of Forces Transmitted via Integrins and the Cytoskeleton; Thermodynamics of Mechanosensitivity; Flexoelectricity and Mechanotransduction; Lipid results on Mechanosensitive Channels; useful Interactions of the Extracellular Matrix with Mechanosensitive Channels; MSCL: The Bacterial Mechanosensitive Channel of enormous Conductance; The Bacterial Mechanosensitive Channel MscS: rising ideas of Gating and Modulation; constitution functionality kinfolk of MscS; The MscS Cytoplasmic area and its Conformational alterations upon the Channel Gating; Microbial TRP Channels and Their Mechanosensitivity; MSCS-Like Proteins in crops; providing strength and Amplifying signs in Plant Mechanosensing; MS Channels in Tip becoming structures.

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Extra resources for Mechanosensitive Ion Channels, Part A

Example text

1998). 5) and the abundance of charged groups pointing at the core of the bundle thus indicating a possible instability of its structure.

2002). How do membrane proteins sense water stress? Mol. Microbiol. 44, 889–902. Robinson, R. , and Stokes, R. H. (1959). ‘‘Electrolyte Solutions,’’ 2nd edn. , London. , and Lester, H. A. (2004). Gating transitions in bacterial ion channels measured at 3 us resolution. J. Gen. Physiol. 124, 151–161. , Bass, R. , Rees, D. , and Lester, H. A. (2003). Open‐state disulfide crosslinking between Mycobacterium tuberculosis mechanosensitive channel subunits. Biophys. J. 84, 2357–2365. Smart, O. , Neduvelil, J.

Acad. Sci. USA 89, 4144–4148. , and Rees, D. C. (2003). Structure and mechanism in prokaryotic mechanosensitive channels. Curr. Opin. Struct. Biol. 13, 432–444. 1. , Cortes, D. , and Martinac, B. (2002a). Open channel structure of MscL and the gating mechanism of mechanosensitive channels. Nature 418, 942–948. , Cortes, D. , and Martinac, B. (2002b). Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nat. Struct. Biol. 9, 696–703.

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Mechanosensitive Ion Channels, Part A by Owen P. Hamill (Eds.)

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