By Bohuslav Ost'ádal, Frantisek Kolár
Cardiac Ischemia: From damage to Protection has been divided into six components. the 1st half describes the diversities among hypoxia and ischemia, animal versions, the consequences of ischemia on myocardial functionality and metabolism, and the electrophysiological outcomes of ischemia. the second one half offers with the mechanisms of cardiomyocyte dying in ischemia, structural elements of irreversible ischemic damage, necrosis and apoptosis of cardiac cells, the function of calcium, and the concept that of calcium antagonism. The 3rd bankruptcy is a quick description of reperfusion damage, its medical relevance, and attainable prevention. The fourth half summarizes adjustments in myocardial vasculature in the course of ischemia and reperfusion. The 5th half is the survey of 2 major chances for expanding cardiac resistance to ischemia and hypoxia, i.e. long-lasting edition to power hypoxia and short-lasting preconditioning. The final a part of the booklet bargains with comparative and ontogenetic facets of cardiac sensitivity to oxygen deprivation; this bankruptcy additionally summarizes the ontogenetic modifications and obstacles in endogenous and exogenous safety of the ischemic/hypoxic heart.