By Nancy N. and Ronald J. Kuhr (eds). Ragsdale
content material: Minimizing the chance linked to pesticide use : an summary / Alvin L. younger --
present toxicology standards for registration / Raymond A. Cardona --
Acute as opposed to persistent toxicity and toxicological interactions concerning insecticides / Raymond S.H. Yang --
New methods for using non permanent genotoxicity exams to guage mutagenic and carcinogenic strength / Frederick J. de Serres --
Simulation modeling in toxicology / J.T. Stevens and D.D. Sumner --
Vulnerability of pests : research and exploitation for more secure chemical keep an eye on / Robert M. Hollingworth --
Pests as a part of the environment / L.V. Madden --
rules governing environmental mobility and destiny / James N. Seiber --
Mammalian metabolism / H. Wyman Dorough --
Molecular modeling : a device for designing crop defense chemical compounds / Erich R. Vorpagel --
Pesticide use : the necessity for correct security, software, and disposal / W.K. Hock --
instructing the general public touching on hazards linked to poisonous components / Ronald W. Hart and Angelo Turturro --
Mass media's impression on public perceptions of pesticide possibility : realizing media and enhancing technology assets / JoAnn Myer Valenti --
precis and dialogue / Robert E. Menzer.
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Toxicol. 1983, 3, 114-20. Parker, C. ; Piccirillo, V. ; Kurtz, S. ; Garner, F. ; Gardiner, T. ; Van Gelder, G. A. Fundam. Appl. Toxicol. 1984, 4, 577-586. Dyck, P. ; Schoening, G. ; Lais, A. ; Oviatt, K. ; Sparks, M. F. J . Environ. Pathol. Toxicol. Oncol. 1984, 5, 109-117. Parker, C. ; Patterson, D. ; Van Gelder, G. ; Gordon, E. ; Valerio, M. ; Hall, W. C. J. Toxicol. Environ. Health 1984, 13, 83-97. Hallenbeck, W. ; Cunningham-Burns, K. M. In "Pesticides and Human Health"; Springer-Verlag: New York, 1985; 166 pp.
E. In "Odor Quality and Chemical Structure"; Moskowitz, H. ; Warren, C. ; ACS Symposium Series No. , 1981; pp. 143-160. ; ACS Symposium Series; American Chemical Society: Washington, DC, 1987. 5. STEVENS AND SUMNER 10. 11. 12. 13. 14. 15. 16. 17. 18. Simulation Modeling in Toxicology 51 Jurs, P. C ; Hasan, M. ; Henry, D. ; Stouch, T. ; Whalen-Pederson, E. K. Fund. Appl. Toxicol. 1983, 3, 343. Stuper, A. ; Brugger, W. E . ; Jurs, P. C. In "Computer Assisted Studies of Chemical Structure and Biological Function;" Wiley-Interscience, New York, 1979.
The rationale for t h i s concern was derived from the enzyme i n h i b i t o r y properties of d i s u l f i r a m toward acetaldehyde dehydrogenase. Since t h i s enzyme plays a key role in the biotransformation of EDB, i t was thought that i t s i n h i b i t i o n might modify the t o x i c i t y of EDB, including i t s carcinogenicity. Table III. 05% in diet) EDB + Disulfiram 48 rats/group/sex 18 months 7 hr/day, 5 days/week (inhalation) Diet given ad l i b i t u m except chamber exposure period Body weights Food consumption Mortality Hematology Gross and Histopathology Condensed from Wong et a l .
Pesticides. Minimizing the Risks by Nancy N. and Ronald J. Kuhr (eds). Ragsdale