Read e-book online Trends and Changes in Drug Research and Development: PDF

By S. R. Walker, J. A. Parrish (auth.), Dr Bryan C. Walker, Professor Stuart R. Walker (eds.)

ISBN-10: 0852008392

ISBN-13: 9780852008393

ISBN-10: 9400926596

ISBN-13: 9789400926592

ISBN-10: 9401076987

ISBN-13: 9789401076982

The twentieth Anniversary of a realized Society is a momentous occasion in its af­ gala's, and it's becoming that, within the Appendix to the lawsuits of the 20 th An­ niversary assembly, the heritage of the Society for Drug study is printed. the purpose of the Society, to inspire an interdisciplinary procedure and to behave as an agency free of any particular clinical department of data, used to be completed and is exemplified through the ebook of those lawsuits of the Anniversary assembly held on the Pharmaceutical Society of serious Britain. in just different circumstances have the Society's lawsuits been released, major­ taining the unique determination and coverage to permit club to get pleasure from com­ munications from those that won't have agreed to talk had book been essential. The papers offered on the Anniversary assembly coated a variety of clinical disciplines, and it's becoming that paintings of such calibre must have been released below the capable editorship of Stuart and Bryan Walker. they need to end up valuable to those that have an interest in Drug Research.

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Additional info for Trends and Changes in Drug Research and Development: Proceedings of the Society for Drug Research 20th Anniversary Meeting held at the Pharmaceutical Society of Great Britain, London 26 September 1986

Example text

19. 20. Modell W. Clinical pharmacology: a retrospective view of its future. Triangle (Sandoz J Med Sci) 1977; 16: 123-7. Prescott L F et al. Drug conjugation in clinical toxicology. Biochem Soc Trans 1984; 12: 96-9. Prescott L F and Highley M R. Drugs prescribed for self-poisoners. Br Med J 1985; 290: 1633-6. Roberts C. Clinical pharmacology. J R Coll Physicians 1986; 20: 103-4. Sheiner L B and Benet L Z. Premarketing observational studies of population pharmacokinetics of new drugs. Clin Phannacol Ther 1985; 38: 481--87.

Clinical pharmacology should be more concerned with the outcome of intervention with drugs and indeed the safe and effective usage of drugs implies measurement of outcome. However the importance of observation and measurement at the bedside shall not be minimized. Both John Oates in the United States and Alisdair Breckenridge in this country have emphasized the importance of critical observation at the time of Phase I studies and government has responded by easing the requirements for clinical trial exemption in this country to facilitate such work.

33 3. REGULAnONS AS SOCIETY'S STANCE ............................................................... 34 4. CONCLUSIONS ............................................................................................................ D. Dayan Why, we must ask, should a meeting of scientists concerned with producing safe medicines, need to discuss what must appear to be a fundamental precept in their work - the importance of animal experimentation in attaining safety? Challenging accepted ideas and techniques is a fruitful part of science, but why should such a basic feature of every biological science now be under violent attack as 'unethical', or at least as 'unnecessary'?

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Trends and Changes in Drug Research and Development: Proceedings of the Society for Drug Research 20th Anniversary Meeting held at the Pharmaceutical Society of Great Britain, London 26 September 1986 by S. R. Walker, J. A. Parrish (auth.), Dr Bryan C. Walker, Professor Stuart R. Walker (eds.)


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